Gene identified in short term memory loss

- Fri, 9 Nov 2007

Scientists believe they have discovered a gene which may be responsible for triggering dementia and severe  memory decline in the elderly. The culprit: the BDNF gene which controls healthy growth of brain cells involved in  memory and higher thinking.

Researchers at the National Institute of Mental Health have found that senior citizens with two normal copies of the gene may be more resilient to age-related changes in the brain than those with one or two mutated versions of the gene. Previous studies among young people have associated a mutation in the BDNF with intelligence. But this latest study, reported in Science Daily, has highlighted that age brings out the problem and that individuals with a BDNF mutation "showed a steeper age-related decline" in memory when compared to those without.

The researchers point out that BDNF may be just one culprit and it is likely that more than one gene is responsible for triggering brain memory loss. But once scientists have identified these genes it would one day be possible to create gene-screening programs for people in middle-age. "It is possible that through early identification of susceptible individuals early intervention through lifestyle changes and other interventions could be facilitated to increase an individuals resilience to the effects of ageing," said the study's co-author Daniel Weinberger, Phd.

One of those techniques Dr Weinberger is referring to is brain exercise. Clinical studies have shown that in the same way that physical exercise keeps our bodies healthy, targeted mental activities can strengthen the brain's pathways associated with memory and concentration. As a result, the brain is more resilient and able to protect itself against age-related memory decline. HeadStrong Cognitive Fitness is the world's leader in producing computer software-based brain training exercises. They are developed by leading neuropsychologist Nicola Gates and endorsed by the internationally renowned authority on cognitive neuroscience, Professor Elkhonen Goldberg, PhD, clinical professor of neurology at New York University School of Medicine. Want to know more? Go to www.headstrong.com